Sunday, March 12, 2023

Rhodanine



Rhodanine is a heterocyclic organic compound with the chemical formula C3H3NOS. It is a yellow crystalline solid that is soluble in polar solvents such as water and ethanol. Rhodanine has a five-membered ring structure with a thione (C=S) group and a ketone (C=O) group in adjacent positions on the ring.
Rhodanine derivatives have been studied for a wide range of biological activities, including anticancer, antiviral, and antifungal properties. They have also been investigated as potential agents for the treatment of Alzheimer's disease, diabetes, and obesity. In addition, rhodanine and its derivatives have been used as precursors for dyes, pigments, and other organic compounds.
Rhodanine can be synthesized by the reaction of thiosemicarbazide with a ketone or aldehyde in the presence of an acid catalyst. The resulting product can be purified by recrystallization from a suitable solvent.




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